A research team has unraveled the three-dimensional structure and molecular mechanism of ATP citrate lyase (ACLY). This is a central metabolic enzyme -- a protein that accelerates chemical reactions - ...
Once daily oral administration of 326E, a novel liver targeted ACLY inhibitor, ameliorates hypercholesterolemia and atherosclerosis by reducing hepatic de novo lipogenesis and increasing hepatic ...
Esperion announced the expansion of its development portfolio with a new program aimed at treating primary sclerosing cholangitis (PSC), a rare liver disease. The company confirmed the effectiveness ...
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