Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to ...
Thyroid hormones play a fundamental role in cardiovascular function. They influence how the heart responds to adrenaline, how ...
BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
Cardiac fibrosis impacts millions of patients and currently has no effective therapy. Stanford Cardiovascular Institute researchers have uncovered a new mechanosensing-based mechanism that reduces ...
The adult mammalian heart bears limited regenerative capacity, resulting in the irreversible loss of cardiomyocytes post-cardiac injury, and often culminating in end-stage heart failure. Cardiomyocyte ...