The numerous cells that make up mammalian tissues are surrounded by an intricate network of proteins known as the extracellular matrix (ECM). Together, these proteins provide cells with a structural ...

Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.