A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

A detailed map of human chromosomes within the nucleus is presented in Nature this week. This resource provides a foundation for an improved understanding of how the physical layout of human DNA is ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 5 (February 4, 2020), pp. 2241-2242 (2 pages) D. Krepel, A. Davtyan, N ...

Chromosome with loops (on the left) and the peak-dip derivative curve of the contact probability (on the right). On large and small scales, chromosome folding differs significantly due to the ...

A research team led by André Marques at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, has uncovered the profound effects of an atypical mode of chromosome arrangement on ...

This study is led by Prof. Shunxin Wang (State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, ...

A research team has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution. A research team led by André Marques at the Max Planck Institute ...

In about one out of every 800 people, two chromosomes fuse together to form an unusual bond. These are known as Robertsonian chromosomes. It's a mystery that has long stumped scientists. Now, ...