Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...
Researchers in the Center for Immunotherapy at Roswell Park Cancer Institute (RPCI) have evaluated the human leukocyte antigen (HLA), a group of genes that help regulate the body's immune system, for ...
A multi-institutional study led by a Massachusetts General Hospital (MGH) investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, ...
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients. While the gene HLA-B*58:01 has long ...
—Researchers provide the most comprehensive genetic synopsis of primary biliary cholangitis to date, identifying 44 risk-associated variants with strong evidence for novel genome-wide significant loci ...
Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records Accurate human leukocyte antigen (HLA) typing is an essential step for designing ...
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