Figure 1: Dependence of ROS formation activated by PtdIns(3,4,5)P 3 and PtdIns(3)P on purified components. Figure 2: PtdIns(3)P activates a relipidated oxidase complex in the presence of p40 phox. Pig ...
Genetic and mutational heterogeneity of autosomal recessive chronic granulomatous disease in Tunisia
NADPH oxidase is the key enzyme for the inducible production of superoxide (O − 2) and superoxide-derived reactive oxygen species in phagocytes and plays a crucial role in host defence mechanisms ...
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