Common conditions such as indigestion and heartburn, as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers involve disruptions of the normal activity of parietal cells (PCs ...

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal ...

Left: In normal gastric tissue, gastric epithelial cells rely on growth signals provided by the surrounding microenvironment. In particular, WNT signals — such as WNT2 secreted by neighboring cells — ...

Researchers studied stomach and duodenal ulcers in a large research project comparing Japanese and European populations. They found 25 new genetic markers linked to ulcers which showed that, though ...

Researchers have identified molecular and genetic pathways that direct the generation and maturation of parietal cells, the only cells in the body that produce acid, from stem cells. The findings can ...