Judge Richard Pacheco heard multiple cases involving people struggling with substance use disorder, highlighting the challenges courts face in balancing accountability, treatment and public safety, ...

John F. Kelly, PhD, of the Recovery Research Institute and Department of Psychiatry at Mass General Brigham, is the lead ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Alcohol use disorder (AUD) is one of the leading causes of preventable death in the United States and worldwide, and leads to substantial disease and medical complications. While treatments are ...

Substance use recovery is a lifelong process, but environmental triggers, such as alcohol at social gatherings or pain medication advertisements, can put individuals in recovery at risk of relapse.

Substance use disorder is a universal, complex health condition that manifests as the uncontrollable consumption of alcohol ...

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain-and offers insights on developing drugs to treat this condition.

Research on the biological basis of addiction published in Biological Psychiatry uncovers the critical role that the HDAC5 enzyme plays in gene expression in the brain's epigenetic mechanisms that ...