The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

DNA’s elegant double helix isn’t just beautiful—it’s a masterclass in precision engineering. From base pairing to semi-conservative replication, every step ensures life’s blueprint is copied ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular ...

Latest research highlights advances in single-molecule biophysics. It focuses on how scientists observe DNA-protein interactions in real time using Single-Molecule Imaging. One key method involves ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer. Drs Ursula A. Matulonis and Panagiotis A. Konstantinopoulos discuss ...

A newly described small molecule inhibitor called AOH-1996 targets a cancer-associated isoform of PCNA (caPCNA), leading to a very broad therapeutic window. Researchers at City of Hope, a cancer ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...