New AACR data highlight stenoparib’s potential in colorectal cancer through WNT pathway modulationThe Stenoparib-DRP® companion ...

Wnt/β-catenin signaling is central to bone biology, craniofacial development, and broader tissue engineering applications. Identifying SMAD7 as a direct transcriptional partner of β-catenin opens ...

Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have increased year by year. HCC research has increasingly focused on ...

Fig. 1: Wnt ligand expression promotes liver metastasis of gastric cancer. Two gastric organoid lines, KTP and WKTP were established from mouse stomach epithelium. KTP organoids carry driver mutations ...

A new preclinical study from Weill Cornell Medicine found that the protein caspase-5 (CASP5), long thought to be a foot soldier in the body's defense ...

Iterion Therapeutics announced that two abstracts featuring its first-in-class TBL1 inhibitor, tegavivint, will be presented at the 2026 American Association for Cancer Research (AACR) Annual Meeting.