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  1. Sickle Cell Disease (SCD) Symptoms, Causes & Types

    Aug 13, 2025 · Sickle cell disease (SCD) is an inherited blood disorder. It causes your red blood cells to form into a “C” shape. It can cause pain and serious complications.

  2. About Sickle Cell Disease | Sickle Cell Disease (SCD) | CDC

    Feb 21, 2025 · Sickle cell disease (SCD) is a group of inherited blood disorders. Abnormal hemoglobin is produced. Red blood cells become hard and sticky and get stuck in small blood vessels, resulting …

  3. Sickle Cell Disease - Johns Hopkins Medicine

    What is sickle cell disease? Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin …

  4. Home - SCDAA

    Since 1972, our organization has been on the forefront of improving the quality of health, life and services for individuals, families and communities affected by this rare disease and related …

  5. What Is Sickle Cell Disease? - NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

  6. Sickle Cell Disease (SCD): Symptoms, Causes, and Treatment

    Sep 28, 2025 · Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells. Common symptoms include anemia, fatigue, severe pain, and swelling.

  7. Sickle-cell disease - World Health Organization (WHO)

    Aug 6, 2025 · Sickle-cell disease (SCD) is a genetic disorder that affects haemoglobin, the molecule in red blood cells responsible for carrying oxygen. The disease causes red blood cells to become rigid …

  8. Sickle Cell Disease (SCD) | Sickle Cell Disease (SCD) | CDC

    Find sickle cell disease-related data and statistics on prevalence, complications, and more. Find fact sheets, toolkits, infographics and more on sickle cell disease and sickle cell trait. Learn the steps …

  9. Sickle Cell Disease Fact Sheet - NHLBI, NIH

    Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD.

  10. Sickle Cell Disease | Sickle Cell Anemia | MedlinePlus

    Sep 6, 2024 · What causes sickle cell disease (SCD)? SCD is caused by a variant (change) in a gene that has instructions for your body to make one part of the hemoglobin. This changed gene is …