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Peristalsis is how the colon moves contents through the digestive system. These wave-like muscle contractions push material along the large intestine — mixing it, absorbing water, and eventually moving waste toward the rectum. This process is controlled by the enteric nervous system, sometimes called the "second brain" of the gut. It works independently, adjusting motility as needed — slow, rhythmic, and highly coordinated. This animation shows peristalsis in the colon based on SciePro’s 3D anat
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